Approximately 140,000 second trimester abortions are performed in the US each year. Second trimester abortion is most commonly performed by a technique known as dilation and evacuation. Clinicians use digoxin, a drug commonly used for cardiac conditions, to facilitate pregnancy termination in the late second trimester. When injected into the fetus or amniotic fluid, digoxin ...Read more >

Background: Globally there is a dearth of access to safe second trimester abortions. Preoperative cervical ripening improves the safety of these procedures. Prior clinical and pharmacokinetic studies suggest misoprostol and Dilapan-S are effective for faster cervical ripening, allowing early second trimester abortions to be performed in a single day. However, it is unknown which agent ...Read more >

Objective: To explore women’s preferences for pain control during first-trimester surgical abortion. Methods: This was a qualitative study that employed pre- and post-operative semi-structured individual interviews to understand women’s decision making process surrounding pain control for first-trimester surgical abortion. Interviews were taped, transcribed, and are being independently coded by two study investigators to establish a ...Read more >