As access to legal abortion in the formal healthcare system becomes more restricted across the United States (U.S.), there has been increased focus on understanding the ways that individuals may seek care outside of the healthcare system, including through self-managed abortion (SMA). SMA refers to any action taken to end a pregnancy outside of the formal healthcare system, and includes self-sourcing mifepristone and/or misoprostol, consuming herbs or botanicals, ingesting toxic substances, and using physical methods. SMA can also involve a range of interactions with community support, the formal healthcare system, and clinicians. It is essential that clinicians are aware of the expected course of SMA with medications and its rare complications, complications of other potentially less safe or effective methods, and other nonmedical risks involved in SMA Clinicians should advocate for the repeal or reform of any laws used to criminalize patients for SMA and other pregnancy outcomes, as well as against measures that undermine the privacy of patient information. Clinicians should be aware that increasing stigma and scrutiny around abortion increase the likelihood that patients will face criminalization. Clinicians should clearly communicate with all members of the healthcare team, including social work, nursing, and other staff, about the importance of pushing back against the criminalization of patients. Healthcare professionals must commit to mitigating risk for their patients and provide abortion care and miscarriage management that does not put their patients at risk of being targeted by the criminal legal system. When possible, hospitals (or hospital departments) should devise a protocol for treating pregnancy complications that provides the maximum protection possible for patient privacy.