Extracellular heat shock protein 10 (Hsp10): Is it a better marker than human chorionic gonadotropin (hCG)?
Awarded 2024
Uta Landy Complex Family Planning Scholars
Rachel Shin, MD, MPH
Oregon Health & Science University

Rachel Shin, MD, MPH is completing her first year of Complex Family Planning Fellowship at Oregon Health & Science University (OHSU). She received her MD at Virginia Commonwealth University and completed her MPH at Harvard T.H. Chan School of Public Health, where she studied Global Health with a Maternal and Child Health focus. She completed her OB/GYN residency training at Cleveland Clinic Foundation. Her research interests include rapid detection of pregnancy resolution, telemedicine in abortion and contraceptive counseling, and sexual and reproductive health attitudes among Asian American Native Hawaiian Pacific Islander individuals.

Her fellowship thesis project is focused on investigating a known protein characterized post-pregnancy but has been overlooked for decades due to the cumbersome assay used to analyze it. Hsp10 appears to be a better surrogate for faster identification of pregnancy completion than the gold standard, hCG testing. The proposed study will be the first to describe Hsp10 serum concentrations utilizing modern commercially available assays as well as testing for Hsp10 in the urine. The target patient population for these initial studies are patients post-medication abortion but there are numerous indications where our findings would have the potential to significantly change clinical practice.